李揚,博士,碩士生導師,校聘副教授
地址:武漢市東湖新技術開發區光谷一路206号,77779193永利官网
郵編:430205
郵箱: lyyy9281015@163.com,lyyy928@foxmail.com
教育背景
2017/09-2022.06,武漢大學,藥學,博士
2013/09-2017/06,77779193永利官网,制藥工程,學士
工作履曆
2024/08-至今,77779193永利官网,校聘副教授
2022/07-2024/07,華東理工大學,博士後
科研項目
1. 國家自然科學基金青年項目,22307036,30萬,主持
2. 中國博士後科學基金面上項目,2023M731079,8萬,主持,已結題
3. 上海市超級博士後資助項目,2022161,30萬,主持,已結題
4. 77779193永利官网科學基金,10萬,主持
研究領域
藥物化學:診療探針與藥物遞送
化學生物學:光學探針(如熒光和磷光探針等)與生物成像/傳感
精細化工:有機功能染料(如近紅外熒光與有機室溫磷光材料等)
代表性論文:
[1] Yang Li, Xiang Ma* et al. Activatable red/near-infrared aqueous organic phosphorescence probes for improved time-resolved bioimaging. National Science Review, 2025, 12, nwae383. (一區top, IF= 16.3)
[2] Yang Li, Xiang Ma* et al. Aqueous up-conversion organic phosphorescence and tunable dual emission in a single-molecular emitter. Chemical Science, 2025, Doi: 10.1039/D4SC08330J. (一區top, IF= 7.6)
[3] Yang Li, Xuechuan Hong, Yuling Xiao* et al. Organic NIR-II dyes with ultralong circulation persistence for image-guided delivery and therapy. Journal of Controlled Release, 2022, 342, 157-169. (一區top, IF= 10.5)
[4] Yang Li, Xuechuan Hong*, Yuling Xiao* et al. Self-assembled NIR-II fluorophores with ultralong blood circulation for cancer imaging and image-guided surgery. Journal of Medicinal Chemistry, 2022, 65, 2078–2090. (一區top, IF= 6.9)
[5] Yang Li, Xuechuan Hong* et al. Small-molecule fluorophores for NIR-IIb imaging and image guided therapy of vascular diseases. CCS Chemistry, 2022, 4, 3735–3750. (一區top, IF= 9.4)
[6] Yang Li, Xuechuan Hong and Yuling Xiao* et al. Novel NIR-II organic fluorophores for bioimaging beyond 1550 nm. Chemical Science, 2020, 11, 2621-2626. (一區top, IF= 7.6)
[7] Yang Li, Xuechuan Hong* et al. A bright NIR-II fluorescence probe for vascular and tumor imaging. Journal of Visualized Experiments, 2023, e64875.
[8] Yishen Liu, Yang Li, Xuechuan Hong* et al. Versatile Types of Inorganic/Organic NIR-IIa/IIb Fluorophores: From Strategic Design toward Molecular Imaging and Theranostics. Chemical Reviews, 2022, 122, 209–268. (共同一作,一區top, IF= 51.5)
[9] Qihang Ding, Xiaoyu Xu, Yang Li, Jong Seung Kim* et al. Diverse interactions between AIEgens and biomolecules/organisms: Advancing from strategic design to precision theranostics. Chem, 2024, 10, 2031-2073. (共同一作,一區top, IF= 19.1)
[10] Xue Qiao, Yang Li, Xuechuan Hong* et al. A near-infrared IIb fluorophore for in vivo imaging and image-guided therapy of ischemic stroke. Dyes and Pigments, 2023, 212, 111123. (共同一作)
授權專利
申請中國專利6件,已獲批4件
1. ZL202110115536.8,可調控代謝的有機熒光小分子化合物及其制備方法和應用
2. ZL202110115537.2,可在體内長時間循環的有機熒光小分子化合物及其制備
3. ZL202110748816.2,具有聚集誘導發光性質的近紅外二區熒光化合物及其制備方法和應用
4. ZL202110749756.6,1500 nm以上發射熒光的有機熒光小分子化合物的制備和應用